According to Dr. Keppler, alcohol is the most accessible and commonly used and abused drug by people of all ages. In terms of being harmful to your health, it is also the substance that people think of least. But the reality, as shown in this series, is that alcohol is far from harmless. Computer graphics and brain scans illustrate precisely what alcohol is capable of inside the human body.

Part One focuses on alcohol's effects on the pharynx, throat, stomach, pancreas, and liver. Dr. Keppler explains that alcohol's unique tendency to remain in the body considerably longer than other drugs bathes these organs in toxic material for extended periods. A bonus Q&A segment follows.